R John Collier Selected Research

anthrax toxin (anthrax lethal factor)

6/2013	Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen.
2/2008	Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature.
10/2007	Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth.
11/2005	Whole-cell voltage clamp measurements of anthrax toxin pore current.
9/2005	A soluble receptor decoy protects rats against anthrax lethal toxin challenge.
9/2005	Receptor-specific requirements for anthrax toxin delivery into cells.
11/2004	Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin.
5/2004	Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen.
5/2002	The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen.
1/2002	Mapping the anthrax protective antigen binding site on the lethal and edema factors.

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R John Collier Research Topics

Disease

13	Anthrax 01/2022 - 08/2003
8	Edema (Dropsy) 01/2022 - 01/2002
7	Neoplasms (Cancer) 06/2013 - 04/2004
1	Pain (Aches) 01/2022
1	Infections 05/2015
1	Inflammation (Inflammations) 04/2008
1	Inhalation anthrax 09/2005
1	Communicable Diseases (Infectious Diseases) 09/2003

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2003
11	AntigensIBA 01/2022 - 05/2002
10	anthrax toxin (anthrax lethal factor)IBA 06/2013 - 01/2002
3	anthrax toxin receptorsIBA 09/2005 - 04/2004
2	Bacterial ToxinsIBA 01/2022 - 08/2003
2	VaccinesIBA 05/2015 - 09/2003
2	Virulence Factors (Pathogenicity Factors)IBA 04/2013 - 07/2009
2	Adenylyl Cyclases (Adenylyl Cyclase)IBA 04/2008 - 01/2003
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2008 - 02/2008
1	Formaldehyde (Formol)FDA Link 01/2022
1	edema factorIBA 01/2022
1	Botulinum Toxins (Botulinum Toxin)IBA 01/2022
1	CarrageenanIBA 01/2022
1	Immunotoxins (Immunotoxin)IBA 06/2013
1	Trastuzumab (Herceptin)FDA Link 06/2013
1	Caveolin 1IBA 10/2010
1	early endosome antigen 1IBA 10/2010
1	enhanced green fluorescent proteinIBA 10/2010
1	Transferrin (beta 2 Transferrin)IBA 10/2010
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 04/2008
1	AntitoxinsIBA 09/2005
1	AcidsIBA 11/2004
1	Amino Acids FDA Link 04/2004
1	MetalsIBA 04/2004
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2003

Therapy/Procedure

2	Therapeutics 01/2022 - 06/2013
1	Analgesia 01/2022